Prevention Research Center In the Department of Medicine

The Effects of Soy Isoflavones on the Breast, Prostate, and Bone

Isoflavones are a major class of plant estrogens, or phytoestrogens, and are found at high levels in soybeans. Extensive research on the potential health benefits of phytoestrogens has suggested a protective action of soy isoflavones against breast and prostate cancer, osteoporosis, cardiovascular disease, and menopausal symptoms.

Despite these health claims, most of the dietary soy products and isoflavones have not undergone adequate human testing. The proposed research project seeks to establish the basic pathways and mechanisms of isoflavone actions that underlie the effects on the breast, prostate, and bone-loss.

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